Significance of Microalbuminuria in Long-Duration Type 1 Diabetes

Significance of microalbuminuria in long-duration type 1 diabetes.

OBJECTIVE The value of microalbuminuria (MA) in predicting renal disease and premature mortality in longer duration type 1 diabetes is unclear. RESEARCH DESIGN AND METHODS We followed 135 patients with long-standing type 1 diabetes (>30 years' duration) over a 7-year period, recording albuminuria and other clinical variables. Vital status was ascertained and cause of death was recorded. RES...

Microalbuminuria and mortality in long-duration type 1 diabetes.

OBJECTIVE Microalbuminuria is a recognized risk factor for increased mortality and renal failure in type 1 diabetes. Whether it remains a powerful predictor in patients with a long duration of type 1 diabetes is not known. We ascertained the prognostic significance of abnormal urinary albumin excretion in a cohort of patients with at least 30 years of type 1 diabetes. RESEARCH DESIGN AND METH...

Microalbuminuria in Type-1 diabetes mellitus.

Electrocardiographic abnormalities in individuals with long-duration type 1 diabetes.

RESEARCH DESIGN AND METHODS — The study was population based. It consisted of survivors of a cohort (identified in 1979–1980) who were diagnosed with diabetes before 30 years of age, taking insulin, and receiving care in 11 counties in Wisconsin (5). The institutional review board approved the study, which conformed to the principles of the Declaration of Helsinki. Informed consent was obtained...

Endothelial dysfunction is correlated with microalbuminuria in children with short-duration type 1 diabetes.

P atients with diabetes have increased risk of developing atherosclerotic diseases (1). In type 1 diabetes, vascular complications are more frequently identified after the 5th year of the disease. Ultrasound assessment of endothelial function is a noninvasive method for detecting early structural and functional atherosclerotic process in the arterial wall. Impaired flow-mediated dilatation (FMD...